Abstract: Objective To investigate the efficacy of poly (L-lactic acid) application in the rejuvenation of hands, and to analyze the safety of its application. Methods two subjects with aging problems of the hands were given subcutaneous injections of poly-L-lactic acid for hand filling improvement treatment, a detailed protocol of improving treatment was developed and treated, the status of hand improvement in subjects was followed up after treatment, and standardized hand photographs were taken as a contrast basis. Results after 2 month of young onset hand repair surgery on the two propositi, the veins and prominence of the bones of the hand improved significantly in the two propositi, the darker skin complexion state improved, and the collagen content of the hand improved, with gradual fullness of the fingers in subject 1. Three months after the young onset repair surgery, the skin quality of the hand improved significantly more finely in subject 2, and the darker skin complexion problem had largely disappeared, with the bones remaining intact in the two propositi, The venous prominence problems had largely disappeared, the collagen content of the hands had improved significantly, the finger morphology of patient 1 and the problems of dark finger joints had all improved significantly, and none of the 2 subjects had related complications, and the 2 subjects had high satisfaction with the young treatment of polylactic acid hand. Conclusions the use of poly-L-lactic acid in revision treatment of hand rejuvenation has shown remarkable results and a good safety profile. Keywords: Poly-L-Lactic Acid; Younger Age of Hands; Dermal Filling; Safety Preface; Löviselle




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Introduction: Poly-l-lactic acid (PLLA) and micro-focused ultrasound (MFU) are widely used for skin rejuvenation, each promoting collagen remodeling through distinct mechanisms. While combined use is common in practice, the optimal treatment sequence